Causes:

• Hypotension- low blood pressure.
• Organ failure – heart, liver.
• Blood or fluid loss -bleeding or diarrhea.
• Heart attack, heart failure- conditions leading to acute decreased heart function.
• Sepsis- life-threating infection.
• Multiple myeloma- type of cancer.
• Vasculitis – a rare condition causing inflammation and scarring on microscopic capillaries making them stiff, narrow, and weak.
• Scleroderma- diseases that affect the connective tissue that supports your internal organs.
• Tubular necrosis, glomerulonephritis, thrombotic microangiopathy- conditions that cause inflammation or damage to the kidney tubules in the small vessels in your kidneys.
• Overuse of NSAID, pain medicines like ibuprofen, ketoprofen, naproxen, used to reduce headaches, swelling, and pain.
• Major surgery.
• Trauma- burns, gunshot wounds, falls.
• Severe allergic reactions.
• Obstruction of urine – acute benign prostatic hyperplasia (out flow of urine out of the bladder), cystocele, bladder neck obstruction.